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While valid testosterone replacement therapy may promote weight loss in obese men, anabolic steroid misuse is not a recommended weight loss strategy. Additionally, women who misuse anabolic steroids are at high risk of developing the reproductive toxicity of the drug and should be treated only when there is a clinical indication, according to a National Institutes of Health (NIH) report . Research suggests that steroid misuse during pregnancy is not associated with fetal brain damage, but recent studies suggest that steroid misuse during lactation may impair cognitive performance.1 However, there is no clinical literature evaluating the long-term health effects of steroid misuse. According to a survey of 1,000 women of reproductive age, women who misused steroids for an average of 12 years had more than twice the risk of having a baby who was overweight or obese with low birth weight as compared with women who had never misused steroids, oral steroid spray.2 In other words, many of the women who misused steroids were using the drugs for years and not just during pregnancy, oral steroid spray. There is an increased rate of steroid misuse in the United States in comparison to several European countries,3,4 but the risk is higher in some communities. In the city of Minneapolis, Minnesota, there were 10 reported cases of steroid misuse per 1,000 women during 2009, whereas the national rate was only 2, oral loss steroid weight.8 per 1,000 woman, oral loss steroid weight.5 Steroid misuse is defined as use of anabolic- androgenic steroids for at least a minimum of 3 years, often for years, from birth to age 28.7 The majority of women who misuse steroids report having been used before or during pregnancy. As is common in women who misuse certain products during their lifetime, the majority of women misuse anabolic steroids and are not se